Can you count on Indian Medicines for Quality and Efficacy?

“I don’t trust Indian Medicines” said the person seating next to me on the flight. The Gentleman was traveling to Newyork. To cut the journey short and my honest need to educate the man I asked him”

Do you know that the largest number of USFDA manufacturing facilities outside the USA are in India?

India is a prominent exporter of Generic pharmaceutical medicines to the USA.
In fact, India is said to be the Pharmacy of the world.

Hearing this the Gentleman got more defensive, He said he read in the newspaper that Children died in some countries in Africa after consuming the syrup of a pharmaceutical company from India and also there was a similar incident in some parts of the country named Uzbekistan.

“Sure that is true and terrible and such companies should be heavily penalized and the promoters should be behind the bars,” I said.

“But you can judge the Indian companies providing quality medicines at the most affordable rates,” I said.

Those companies have a proven track record of serving for many years and that is one of the noble deeds to help mankind.

He said well he did not know that India has such good companies too.

India is a developing country yet has many leading Pharmaceutical companies like Sun Pharma, Zydus, Biocon, etc to name a few which are present in the USA and other first world countries and giving the best Pharmaceutical medicines to the citizens.

“Never judge the book by its cover,” I said and ended the discussion.

Pharmaceutical Companies in Columbia.

According to forecasts, the global pharmaceutical tablet delivery market is predicted to grow at a Compound Annual Growth Rate (CAGR) of 6.4% during the projected period, with an expected market value of USD 1,694.7 billion by 2023. The market’s expansion is fueled by various factors, including the rising prevalence of chronic illnesses, the biologics industry’s growth, and technological advancements. Colombia is becoming an increasingly attractive market for pharmaceutical tablet manufacturers due to its growing interest in research and development and its continuing economic growth. Here is a list of Pharmaceutical companies working in Colombia.: Procaps Laboratories, Aetos Pharma Private Limited, Axon Pharma, Interchem, Vesalius Pharma, Farma Capsules, Xinetix Pharma, Mundi Pharma, Scandinavia Pharma, and Closter Pharma. Each of these companies has a unique focus and objective, ranging from innovative marketing strategies to customer satisfaction and patient health.

Branded Vs Generic Medicines?

Navigating the world of pharmacology can be overwhelming for healthcare providers and patients alike due to the vast number of brand name and generic drugs available. While patients may be prescribed a medication at their appointment, they may be surprised to find a different name on their prescription bottle when they get home. It’s important for healthcare providers to help patients understand the difference between brand name and generic drugs to ensure they are comfortable with their prescriptions.

Although brand name and generic drugs contain the same active ingredient, have the same level of safety and efficacy, and may have different appearances, the inactive ingredients are typically different, as are their costs. Healthcare providers may refer to a drug by its brand name, but they will most likely prescribe the generic version. In fact, state laws require pharmacies to fill the generic version of a drug unless the healthcare provider specifies otherwise, as the generic version is usually less expensive.

The cost difference between brand name and generic drugs can be attributed to the drug development process. Pharmaceutical companies spend a significant amount of money on research, development, and clinical trials to obtain a US patent and market the drug to the public. Once the patent expires, other pharmaceutical companies can produce their own version of the drug, known as a generic version, without incurring the same research and clinical trial costs. This creates competition in the market and drives prices lower.

If a medication is only available in the brand name form, it may be very expensive and not covered by insurance. Healthcare providers can appeal to insurance companies for coverage, but pharmaceutical companies may also offer coupons to help offset the cost. It’s important for patients to ask questions about their medications and for healthcare providers to practice informed-decision making when it comes to prescribing brand name and generic drugs. While pharmaceutical companies aim to make a profit, they also prioritize improving the quality of healthcare through drug development.

Role of Dexamethasone in hospitalised patients in Covid-19.

A study was conducted to determine whether dexamethasone, a steroid, could reduce mortality in hospitalized Covid-19 patients by reducing lung damage caused by inflammation. The study involved randomly assigning patients to receive either dexamethasone or usual care. The primary outcome was 28-day mortality. The study found that patients who received dexamethasone had a lower mortality rate than those who received usual care, especially among patients who required respiratory support at the time of randomization. Specifically, patients who received invasive mechanical ventilation or oxygen alone had a lower mortality rate than those who received usual care. However, patients who did not require respiratory support did not show a significant difference in mortality between the two groups. The study was funded by various organizations and registered under and ISRCTN.

Is cord blood banking a scam?

Cord blood banking is a rapidly growing industry in India, with 15 private banks offering the service of harvesting and storing cord blood for future use. Cord blood contains stem cells similar to those in bone marrow and can be used for treatment if the child ever falls ill with certain diseases. However, the cost of cord blood banking in India is quite high, with prices ranging from Rs.50,000 to Rs.100,000 and some banks charging an annual fee. Additionally, there is concern about the ethics of the industry, with reports of unethical marketing tactics and inflated promises by largely unregulated banks. This has led top medical researchers to call for tighter control to protect gullible parents from being exploited by what they consider to be a money-making scam.

Despite the surge in popularity of cord blood banking, top stem cell researchers and professional bodies of gynaecologists have expressed concerns about the industry. They are alarmed by the unethical marketing tactics and inflated promises by the largely unregulated banks. Furthermore, they argue that private banking of cord blood may be considered “only if there is a high-risk family medical history of disease(s) currently treatable by cord blood”. Other hard facts that banks do not reveal to their subscribers include the possibility that the cord blood of a newborn may not contain stem cells in sufficient numbers to be useful in adulthood, and one’s own stem cells are not useful to treat genetic disorders as they will have the same genetic flaws that caused the disease in the first place. For these reasons, some countries like Italy and France have banned private banking of cord blood. The American Academy of Pediatrics and the Society of Obstetricians and Gynaecologists of Canada discourage this practice while encouraging the storing of cord blood in public banks that store cord blood free of cost and charge only when released for treatment.

Treatment for HIV and AIDS.

Although HIV cannot be cured, highly effective treatments are available that allow most people with the virus to live a long and healthy life.

In the event of possible exposure to HIV, post-exposure prophylaxis (PEP) medicine may prevent infection. PEP should be initiated within 72 hours of contact with the virus, and is only recommended in cases of higher-risk exposure, especially where the sexual partner is known to be HIV-positive. PEP involves taking HIV medication daily for a month and may have side effects. PEP can be obtained from sexual health clinics, genitourinary medicine (GUM) clinics, hospitals, or HIV clinics.

If diagnosed with HIV, regular blood tests will be done to monitor the progression of the infection before starting treatment. Two important blood tests are the HIV viral load test, which measures the amount of HIV virus in the blood, and the CD4 lymphocyte cell count, which measures how the HIV has affected the immune system. Treatment can begin at any time following diagnosis, based on consultation with an HIV doctor.

Antiretroviral medicines are used to treat HIV by preventing the virus from replicating in the body. A combination of drugs is used because HIV can quickly adapt and become resistant. Some HIV treatments have been combined into a single pill, known as a fixed dose combination. People with newly diagnosed HIV typically take between one and four pills per day, and different combinations of medicines are tailored to each person. The effectiveness of treatment is measured by the amount of HIV virus in the blood, which should become undetectable within six months of starting treatment. However, many of the drugs used to treat HIV can interact with other medications, so it is important to consult with a healthcare provider before taking any other medicines

Please note: The above article is just an opinion. Always seek advice of a medical practitioner.

Comparing India’s and China’s Pharmaceutical manufacturing.

India is said to be the pharmacy of the world.

The largest number of USFDA manufacturing facilities outside of the USA are in India.

Indian medicines and their manufacturing facilities are trusted in the Western world.

The Indian government has taken steps to grow the API(Active Pharmaceutical Ingredients)manufacturing to lower the dependency on the cheap quality of API from China.

China suffers a bad name and a lack of trust among international drug distributors through offering cheap finished pharmaceutical formulations in the market.

The Chinese government needs to improve the skills and the quality of manufacturing facilities if it wants to match the skills of the Indian Pharmaceutical sector.

However, china scored very badly in the documents and the dossier part in the finished pharmaceutical formulations part.

China passed through its 4th covid wave some time back.

The Chinese social media sites were flooded with people asking for the Indian-made medicines to treat their loved ones.

The social media sites of china give a clear picture of how Chinese citizens prefer Indian medicines.

However, we need to appreciate the Chinese companies in medical devices.

China has supplied cost-effective medical devices to many needy hospitals and institutions at affordable rates.

What are the treatments in modern medicine for the dry skin?

Dry skin is a condition where your skin lacks sufficient moisture which can cause a rough texture, flaking, and scaly patches on the skin. The medical term for dry skin is xeroderma, and it is a very common skin condition. Dry skin can be managed by using moisturizers, but if it persists or keeps coming back, it is essential to seek the advice of a dermatologist. There are different types of dry skin, including contact dermatitis, eczema, seborrheic dermatitis, and athlete’s foot. Dry skin can occur anywhere on the body, but it is commonly found in areas such as the hands, feet, face, and elbows. Dry skin is usually harmless, and it only causes temporary discomfort. However, severe dry skin can lead to the development of painful sores that can get infected. Dry skin is caused by various factors, including age, climate, health conditions, and genetics. To prevent dry skin, it is recommended to use a moisturizer daily and avoid using products that can irritate your skin.

Banish Heartburn and Acid Reflux with Simple Over-the-Counter Antacids and Acid Reducers.

Over-the-counter (OTC) medications are non-prescription drugs that can be purchased without a doctor’s prescription. There are three varieties of OTC medications that are used to treat heartburn and acid reflux.

Antacids work by neutralizing stomach acid, which reduces its effects. Antacids are available in various brands, including chewable tablets, dissolving tablets, and liquids. They can provide quick and short-term relief.

H2 blockers decrease the amount of acid produced by the stomach. Although they don’t provide immediate relief like antacids, their effects last longer. H2 blockers usually take effect within an hour. An example of an OTC H2 blocker is famotidine (brand name: Pepcid).

Proton pump inhibitors (PPIs) lower the body’s acid production. They are effective for heartburn that is not relieved by antacids or H2 blockers. Relief may take longer to appear with PPIs, but it lasts longer. Most PPI forms take a few days to start working. PPIs are especially useful for individuals with chronic heartburn (more than twice a week). Examples of OTC PPIs include omeprazole (brand name: Prilosec) and lansoprazole (brand name: Prevacid 24HR).

Tips for Improved Health Consult your family doctor to find out which medication is appropriate for you. They can inform you about the benefits and drawbacks. Antacids and acid reducers have few side effects, and any that do occur are usually minor and resolve on their own. These side effects may include headaches, nausea, constipation, or diarrhea.

If you have kidney disease, consult your doctor before taking antacids. Unless your doctor advises it, you should avoid antacids containing calcium carbonate or aluminum hydroxide and magnesium carbonate.

If you are elderly or have an immune system issue, talk to your doctor before taking a proton pump inhibitor. PPIs can raise your risk of pneumonia. If you are a postmenopausal woman, PPIs may reduce calcium absorption and raise your risk of osteoporosis. PPIs may also increase the risk of recurrence for people who have previously been treated for Clostridium difficile (C. diff.) infection.

If you are over the age of 55 and require long-term PPI treatment, your doctor may refer you for an EGD (esophagogastroduodenoscopy). This procedure examines the lining of the esophagus, stomach, and upper small intestine. If you have significant reflux, your doctor may also test you for a bacteria called H. pylori before prescribing PPIs.

Things to Keep in Mind Do not use more than one antacid or acid reducer at a time unless your doctor approves. Keep all medications in a cool, dry location that is inaccessible to children. Storing medicines in bathrooms, which are frequently hot and humid, is not recommended since it can reduce their effectiveness before they expire.

When to Consult a Doctor Inform your doctor how the OTC medications are working for you. If your symptoms do not improve or worsen, the doctor may suggest a prescription medication. Long-term use of PPIs should be avoided whenever possible because they can increase the risk of certain health problems, such as osteoporosis, kidney disease, and dementia.

If you experience any of the following symptoms, inform your doctor immediately. They may indicate a more severe condition.

Bloody or black stools Bloody vomit Heartburn that does not improve after two weeks of treatment with OTC medications Difficulty swallowing or pain while swallowing Unintentional weight loss If you have chest pain, shortness of breath, dizziness, and pain in your arms, consult the medical practitioner.

How does Insulin and Glucagon work in our body?

Insulin and Glucagon are hormones produced by the Pancreas that regulate blood glucose levels in the body. They work in a negative feedback loop to maintain balance, where the effects are counteracted by a decrease in function. Insulin directs cells in the body to absorb glucose from the bloodstream, which is used for energy or stored as glycogen for later use. Glucagon signals the liver and muscle cells to convert glycogen back to glucose, which is absorbed by cells for energy production. Imbalances in these hormones can lead to metabolic disorders like hypoglycemia or hyperglycemia, which can have potentially dangerous consequences if left untreated.

Hormones are chemical messengers that help in regulating different functions in the body. Insulin is one of the most important hormones responsible for maintaining glucose levels in the blood. It allows glucose in the blood to enter the cells and provide them with energy. Insulin and glucagon work together to maintain a balance of glucose in the blood, which is necessary for proper body function and metabolism.

The pancreas is the only organ that secretes insulin, and it acts as a self-contained system that responds to changes in blood glucose concentration. Insulin facilitates the entry of glucose into cells by attaching to insulin receptors on the cells, which instruct them to open up and allow glucose to enter. Insulin also instructs the liver to absorb glucose and convert it into storage molecules called glycogen, and it regulates how the body uses and stores glucose and fat.

Glucagon, on the other hand, interacts with the liver to increase blood sugar levels during periods of low blood glucose. It instructs the liver to convert glycogen to glucose, ensuring a steady supply of glucose to the bloodstream between meals and during sleep.

Insulin plays a crucial role in maintaining the level of glycogen and lipid synthesis in the body, regulating the esterification process of fatty acids, and instructing the liver and muscle and fat cells to take in glucose from the blood. An increase or decrease in the concentration of insulin leads to the secretion of hydrochloric acid by parietal cells in the stomach.

In summary, insulin is essential for maintaining glucose levels in the blood, and it works together with glucagon to regulate blood sugar levels in the body.

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